Oxfordshire Science Park to Create 1,000 Jobs

Culham Science Park in Oxfordshire is set to expand, with up to 1,000 new science and technology jobs.

Three new research labs and office space have been discussed at the Abingdon site, and a planning application has been sent to the council. The 1,000 jobs include skilled and unskilled workers, including the construction of the new buildings and the scientists then working in them once they have been completed.

The created jobs are set to expand the workforce at the Science Park by 50%, to near 3,000. Should planning permission be granted, private companies will be invited to move operations to the park, before construction begins. Currently with 2,000 staff and 45 companies, the Culham Science Park is part of Science Vale UK, which includes two other Oxfordshire sites employing over 10,000 people between them. The expanding of the Abingdon site can only boost the area’s scientific centre credentials further.

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CK Science Salary Survey 2013

Your chance to complete the 2013 CK Science Salary Survey is almost over.

Science jobsThe science salary survey will be closing at the end of February so this is the last chance you will have to  take part. It takes only 5 minutes to complete, and your participation will help us understand what the 2012 science salary brackets were. The results of this survey will be published and will help you with your job and salary expectations for 2013.

Click on the link below to complete the CK Science Salary Survey

https://www.surveymonkey.com/s/cksciencesalarysurvey

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New Science park creates over 2000 jobs

ThA new-state-of-the-art Science park will bring 2,000 jobs to Wiltshiree Swindon Advertiser has reported that a new state-of-the-art science park will be developed at Porton in Wiltshire creating more than 2,000 jobs over a 10-year-period and bringing national and international investment into the area.

Wiltshire Council and a joint development company, comprising Trebor Developments LLP and Wrenbridge Land Limited, will develop the science park. The successfully bided  for £10m funding from the Department of Business, Innovation and Skills (BIS). This will help kick-start the first phase of the science park project, creating the infrastructure for the planned 355,000 sq ft science park and a new 23,000 sq ft innovation centre

This new science park will  provide facilities for science- and research-based industries and could attract £70m of private sector investment over the next 10 years.

 

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Pharmaceutical Export Sales Manager – Home working

Jason Johal at CK Science is currently recruiting for a Pharmaceutical Export Sales Manager for an amazing role with an MHRA licensed pharmaceutical manufacturing organisation based in London on a full time, permanent basis.

Responsibilities:

This newly formed Pharmaceutical Export Sales Manager role offers a blank canvas in regards to where you can take it and what you can achieve. It would be ideal for a person with an “explorer” personality and for someone looking for a role with autonomy, challenges and happy to travel globally.

The company are looking for someone that can grow their export business by developing strategies, using current/new contacts within Europe, the Middle East and by utilising their regulatory and pharmaceutical knowledge.

As an Export Sales Manager you will:

  • Develop the overall sales strategy plan for export sales
  • Plan and manage overseas sales through direct customers, distributors and other relevant sales outlets
  • Identify potential partners / distributors / countries for export opportunities
  • Manage export accounts to achieve sales targets, liaising closely with the Sales & Marketing Director, to develop and maximise all sales opportunities
  • Negotiate and manage contracts for sales/ distribution as required to enable effective trading, operations and customer relations
  • Develop knowledge and understanding of local requirements for pharmaceuticals, medical devices and “specials”.
  • Develop export programmes to promote new products and actively support all product promotions to customers
  • Liaise with customers services to process orders, enquiries, sample requests, catalogue requests and offer quotations
  • Deal with customer complaints in a professional and helpful manner
  • Organise and attend customer visits and represent company at trade shows as part of an agreed plan
  • Manage the movement of products in and out of the country in accordance with organisational policy and procedure, and to comply with relevant local, country and international law and process
  • Manage the necessary administration and documentation for the efficient, cost-effective and lawful execution of all export activities. Liaising with regulatory, finance and other departments as required

Qualifications:

The successful applicant for this Export Sales Manager will have the following qualifications, skills & experiences:

  • An experienced Pharmaceutical export sales professional
  • An understanding and experience of setting up distributors in overseas markets
  • Knowledge or experience of the ophthalmology (highly advantageous not essential)
  • The ability to travel for prolonged periods of time
  • A working knowledge of regulatory issues overseas
  • The ability to develop and execute coherent business strategies and plans
  • A detailed understanding of Pharmaceutical industry
  • Be self motivated (minimum supervision required)
  • Strong Communication skills (Verbal and Written)
  • A second European language would be an advantage but is not essential

Benefits:

This Pharmaceutical Export Sales Manager role is a really exciting job for a pharmaceutical sales professional as it offers the opportunity to establish and then develop your own strategies and the freedom to build your career in the direction you want to go.  If successful, you will be joining a Specials Manufacturer with a growing portfolio of branded licensed products coupled with a world renowned reputation. In return there is an attractive salary, coupled with excellent benefits and travel opportunities.

Jason Johal - Pharmaceutical Recruitment

Please contact Jason for more details.

How to apply:

Apply online:

To apply for this Export Sales Manager position, contact Jason Johal via email: jjohal@ckscience.co.uk or 01438 723 500. Please quote reference ST25513 in all correspondence.

 

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GSK invest 10 million euros at their facility in Sligo, Ireland

Pharmatimes have reported that GlaxoSmithKline has decided to keep open its facility in Sligo Ireland and will instead invest 10 million euros into the plant.

GSK acquired the facility in Sligo when GSK bought the dermatology specialist Stiefel Laboratories for up to $3.6 billion in 2009.

There will be some jobs cuts at the plant over the next two years, which currently employs 180 people, with a “gradual” reduction to 120. However, GlaxoSmthKline estimated there would be an additional 50 jobs added in 2014 as the plant improved skills and capacity.

 

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UK stem cell pioneer shares Nobel Prize in Medicine

The BBC has reported that two pioneers of stem cell research have shared the Nobel prize for medicine and/ or physiology

John Gurdon from the UK and Shinya Yamanaka from Japan have been jointly awarded the prize for their work in transforming specialised cells into stem cells, which can become any other type of cell in the body. It is hoped the techniques discovered will revolutionise medicine by using a sample of a person’s skin to create stem cells.

Prof Anthony Hollander, the head of cellular and molecular medicine at the University of Bristol, said: “This joint Nobel Prize traces and celebrates the wonderful scientific journey from John Gurdon’s pioneering early work to the sensational discovery of somatic cell reprogramming by Shinya Yamanaka. It’s fantastic news for stem cell research.”

The prize was awarded this morning at the Karolinska Institute in Sweden, and is the most coveted award in medical science. The Nobel committee said these winners  had “revolutionised” science

 

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Allergans Botox receives UK approval for treatment of MS/spinal injury

CK Science - Scientific Recruitment AgencyPharmaTimes have reported that Allergan’s Botox is now licensed in the UK for patients who have continence issues because of multiple sclerosis or a spinal injury.

The Medicines and Healthcare products Regulatory Agency has give Allergan permission to use Botox (botulinum toxin type A) for managing urinary incontinence caused by neurogenic detrusor overactivity due to subcervical spinal cord injury or multiple sclerosis (MS),

Professor Christopher Chapple, Urology Department, Royal Hallamshire Hospital, Sheffield NHS Trust and a key investigator in the neurogenic detrusor overactivity registration trials, has welcomed the new license, noting that “being able to better control and manage bladder function can be life-changing for patients”.

 

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UCB launches its new biotechnology facility

PharmaTimes has reported that UCB has launched its 65 million euro pilot biotechnology plant in Belgium.

The new facility is located at its Braine-l’Alleud site and will employ 100 employees. This new facility will produce cell culture-based therapeutic proteins that are dedicated to accelerating the availability of new drugs for severe diseases with a focus on the research and clinical trial phases

This new facility is designed enable UCB to improve its biological medicines.

Chief executive Roch Doliveux said that “today, 33% of drugs for human use worldwide are of biotechnological origin and represent more than half of UCB’s current R&D pipeline”. He added that “with this bio pilot plant, we will more rapidly initiate clinical studies of new antibody-based therapeutics”.

 

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Novartis’s rare cancer drug is launched in the UK

Pharmatimes have reported that Novartis have launched their new drug Jakavi which means for the first time patients in the UK with a rare form of blood cancer will now have access to this targeted therapy

Jakavi (ruxolitinib) is a first-in-class JAK 1 and JAK 2 inhibitor, and is now available to treat patients in the UK with disease-related enlarged spleen or various forms of myelofibrosis, which affects around 0.34-0.76 people in every 100,000.

Myelofibrosis is a rare, potentially life-threatening blood cancer characterised by bone marrow failure, enlarged spleen and debilitating symptoms including extreme fatigue, poor quality of life and weight loss, and shortened survival.

Jakavi received EU approval at the end of August 2012

 

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£2.8 billion renewable energy investment in Scotland

Scottish Development International has reported that Scotland’s renewable energy industry has attracted £2.8 billion capital investment since 2009.

Onshore wind accounts for 57 percent of total investment with 21 percent going to offshore wind. The rest of the investment has been deivded between wave and tidal energy, solar photovoltaic, hydro energy, landfill gas and biofuels.

Niall Stuart, chief executive of Scottish Renewables said “These figures show Scotland’s renewables industry is very much bucking the economic trend.  During the downturn our industry has delivered some £2.8bn of much needed capital investment in our economy.  This has helped to grow the supply chain, secure the future of many companies and support more than 11,000 jobs”

 

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GSK,Unilever and Syngenta join alliance as part of the Olympics Global Hunger Summit

The Department of International Development has reported that as part of the Olympic Global Hunger Summit, GSK , Unilever and Syngenta have joined a business alliance to face the growing problem.

The Prime Minister and the Brazilian Vice President, Michel Temer were joined by double Olympic gold medal winner Mo Farah to urge a global drive to boost nutrition.

The two leaders hosted a high-level meeting bringing together representatives from international governments, charities and businesses at Downing Street on the day of the closing ceremony of the London Olympics. They urged the world to take decisive action before the 2016 Olympic Games in Rio to transform the life chances of millions of children by improving their nutrition.

Three new initiatives were announced on these areas, one of these is that some leading UK companies such as Unilever, Syngenta and GSK will work to find ways to make nutritious food available to poor families at prices they can afford.

 

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Grapefruit juice provides anti-cancer benefits

As reported by WorldPharmaNews, results of a clinical trial have showed that a glass a day of grapefruit juice lets patients derive the same benefits from an anti-cancer drug as they would get from more than three times as much of the drug by itself.

Researchers at the University of Chicago Medicine study the effects that foods can have on the uptake and elimination of drugs used for cancer treatment.

In the study, they found that eight ounces a day of grapefruit juice can slow the body’s metabolism of a drug called sirolimus, which has been approved for transplant patients but may also help many people with cancer.

Patients who drank eight ounces a day of grapefruit juice increased their sirolimus levels by 350 percent. A drug called ketoconazole that also slows drug metabolism increased sirolimus levels by 500 percent.

The hope is that this combination could help patients avoid side effects associated with high doses of the drug and reduce the cost of the medication.

 

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Quality Manager – County Durham

Heather Deagle at CK Science is recruiting for an experienced Quality Manager or Qualified Person to work in Sterile production for a major pharmaceutical company based in Durham on a temporary basis initially until the end of the year.

Responsibilities:

The mail function of this Quality Manager role is to provide support for the area on managing issues/deviations to free up time for the Batch Release QP to focus on improvements.

As a Quality Manager you will have the following responsibilities:

  • To lead and direct investigative work into products failing to meet requisite standards (and regulatory issues). Also to develop and agree corrective actions arising from such incidents.
  • Lead deviation investigation clinics, coaching where applicable. To lead, prioritize and provide an effective
  • Product Release Service which ensures that all products released for sale or further processing have a quality appropriate to their intended use i.e. comply with Company GMP standards, Product Quality Specifications and Regulatory requirements.
  • Provide GMP advice on an on going basis
  • Support and influence Quality Improvements to reduce rejects, deviations, complaints and increase productivity.

Qualifications and skills:

The successful candidate for this Quality Manager role will have the following qualifications:

  • Qualified Person status
  • Grad (or equivalent) with several years proven post qualification experience in the pharmaceutical or allied industry
  • Experience in handling regulatory affairs
  • Detailed knowledge of current Good Manufacturing Practice requirements within major pharmaceutical markets.

How to apply:

Apply online:

For more information or to apply for this role please contact Heather Deagle on 0191384 8905 or email hdeagle@ckscience.co.uk. Please quote reference DH24906 in all correspondence.

 

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Olympic Team GB work with scientists on gene tests for injuries

As reported by the BBC, Scientists behind Olympic Team GB are working on genetic tests to understand why some athletes are prone to injury Scientists at the Institute for Human Health and Performance at University College London are currently researching how and why tendon injuries and stress fractures occur as they are common in elite athletes University College London’s Prof Hugh Montgomery says they have found a gene they think strongly influences the risk of stress fracture…….If we understood that genetic component we would have a much better understanding of the patho-physiology – the disease processes that let that happen” The study has been working with the English Institute of Sport (EIS), which aims to apply the latest in sports science and medicine for the benefit of Britain’s Olympic and Paralympic athletes. EIS’s Director of Sport Science, Dr Ken van Someren said “If we can identify some particular genes that are associated with a higher risk of injury in certain individuals, and we think we’re close, we can tailor the training, conditioning and preparation that we put those individuals through.”

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GSK supports Olympics anti doping operation

The Guardian has reported that GSK today marks its role as Official Laboratory Services Provider for the London 2012 Olympic and Paralympic Games by launching its first UK advertising campaign to celebrate the role that anti-doping science will play in helping ensure this summer’s Games are the cleanest possible.

The multimillion-pound ad campaign features a string of British athletes, including Marlon Devonish and Phillips Idowu to highlight its role running the anti-doping testing laboratory for the London Olympic games.

The London 2012 anti-doping laboratory, provided by GSK in partnership with the London Organising Committee for the Olympic and Paralympic Games (LOCOG) and King’s College London opened today and will be operational 24 hours a day, seven days a week. More tests will be carried out at the London 2012 lab, based at GSK’s Harlow site, than at any other Games with every medallist and up to 50 per cent of all competing athletes being tested.

 

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MSD and the Bill & Melinda Gates Foundation announce collaboration to improve family planning

Pharmiweb have reported that MerckSharpeDohme  and the Bill & Melinda Gates Foundation today announced that they will work together to expand access to family planning, a critical step in improving the health of women around the world.

MSD intends to pledge up to $25 million over eight years as part of MSD/Merck for Mothers – the company’s 10-year initiative to reduce maternal mortality around the world. This pledge will be matched by the Gates Foundation as part of its commitment to family planning.

Kenneth C. Frazier, Merck’s chairman and CEO said in the press release that Merck is proud to work in collaboration with the Gates Foundation to help to ensure that many more women around the world have the information and services they need to make practical and informed choices about planning their families……….This important initiative will help us accelerate the work of Merck for Mothers in saving women’s lives.”

 

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GSK & Theravance receive positive data for pill

PharmaTimes have reported that GlaxoSmithKline and Theravance have reported positive data from four Phase III trials assessing a combination therapy for maintenance treatment of COPD, making the once-daily pill closer to a regulatory filing.

The clinical trials involved more than 4,000 patients, including two 24-week efficacy trials comparing a combination of the long-acting muscarinic antagonist (LAMA) umeclidinium bromide and the long-acting beta-agonist (LABA) vilanterol. The date showed statistically significant improvements when compared with placebo and the individual parts in both trials, which tested difference doses.

Darrell Baker, SVP Respiratory Portfolio Optimisation Leader at GSK said “We are very encouraged by the results of these initial studies for our LAMA/LABA, an important cornerstone of our broad respiratory development portfolio…. These studies, together with our earlier dose-ranging work, give us confidence that this is a once-daily medicine with the potential to benefit many patients with COPD.

 

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Bristol-Myers Squibb and AstraZeneca strengthens diabetes alliance

WorldPharmaNews reported that Bristol-Myers Squibb company announced today that they will acquire biopharmaceutical company Amylin Pharmaceuticals Inc.

Following BMS’s acquisition of Amylin, BMS and Astra Zeneca will enter into collaboration arrangements, based on the framework of the existing diabetes alliance, regarding the development and commercialisation of Amylin’s portfolio of products.

AstraZeneca will make a payment to Amylin, as a wholly owned subsidiary of Bristol-Myers Squibb, in the amount of approximately $3.4 billion in cash. Profits and losses arising from the collaboration will be shared equally.

Lamberto Andreotti, chief executive officer, Bristol-Myers Squibb said “The acquisition of Amylin by Bristol-Myers Squibb is also a unique way for Bristol-Myers Squibb and AstraZeneca to expand the alliance between the two companies, and it demonstrates Bristol-Myers Squibb’s innovative and targeted approach to partnerships and business development.

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P&G help London clean up for the Olympics!

SuperSavyMe has reported that P&G has teamed up with the Mayor of London to bring the P&G Capital Clean Up campaign to help clean the capital before the London 2012 Olympic Games

The campaign started in March 2012 and over the last three months, Proctor and Gamble have hosted  a series of clean up events designed to bring Londoners together to spruce up neglected areas of the city as London gears up to host the Olympic games.

The events so far have involved clearing the region of 1,000 bags of litter, removing unsightly graffiti, and restoring swathes of habitat. The public can get involved by signing up to participate in one of the organised clean up events at www.pgcapitalcleanup.com

P&G are official sponsors of the London Olympic Games.

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Leading engineering technology could monitor hip replacements for signs of wear

The Engineer has reported that new leading technology could monitor hip replacements for signs of wear, powered by the movement of the user’s walk.

The device which has been engineered is designed to fit inside a typical prosthetic hip joint, uses a piezo-electric device that generates up to 3.7V of electricity as the user walks to power a strain gauge and a transmitter.   The device contains a ball bearing that rolls back and forth as the user walks along and strikes a substrate covered on one side with piezo-electric material (known as a unimorph) to produce electricity.

Hopefully this new device will be able to tell doctors if the replacement is starting to break down and advise the patient on lifestyle changes or the potential need for another operation. This will hopefully prolong the life of some replacements or at least signal when it is time for a new one, before the patient is in pain.

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