Scientist/Senior Scientist - Assay Development

  • Salary: Competitive
  • REF Number: 00050012
  • Consultant: Naynesh Mistry
  • Contact: 01246 457703
  • Date Published: 22.04.2021
  • Sector: Life Sciences
  • Location: Cambridge, East Anglia
  • Discipline: Biotechnology

CK Group are working in partnership with a growing biotechnology company to recruit a talented Scientist or Senior Scientist with expertise in developing antibody-based assays, to join them at their site based in Cambridge on a permanent basis.

The Company: An exciting opportunity to join a company that is focused on drug discovery and development for protein misfolding diseases. Based in Cambridge, they offer a competitive salary, bonus, pension and health cover.

Scientist/Senior Scientist Role:

  • Assist in running a busy experimental laboratory and contribute to advance the internal research around assay development for toxic oligomer measurements in protein misfolding diseases.
  • Conduct drug discovery research projects.
  • Contribute to the development and application of new methodologies and establishing assays for demonstrating target engagement.

Responsibilities:

  • Use and contribute to the development of antibody-based assays for the direct measurement of protein oligomeric toxic species that are generated during protein aggregation in protein misfolding diseases.
  • Develop ELISA and SIMOA-based assays for assessing protein oligomer levels in a range of samples from in vitro, to cells and ex vivo.
  • Contribute to the automation of such assays.

Your Background:

  • A PhD with extensive experience working in protein chemistry, biochemistry, molecular biology or a related discipline.
  • Extensive experience in ELISA and other antibody-based binding/diagnostic assays.
  • Experience in the recombinant expression (in microbial or mammalian systems) and purification of proteins, in particular antibodies, using a variety of chromatography techniques (e.g. AKTA purification systems, HPLC) and their further characterisation using biochemical and biophysical techniques.
  • Experience in assisting to run a busy biophysical, biochemical or molecular biology laboratory.

Apply: For more information or to apply for this Scientist/Senior Scientist position, please contact Naynesh Mistry on 01246 457703 or email nmistry@ckgroup.co.uk, quoting job ref 50012.

It is essential that applicants hold entitlement to work in the UK.

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