A New Way of Delivering Drugs to the Brain

As reported by the BBC, scientists at the University of Oxford have developed a breakthrough way of delivering drugs to the brain.

One of the main challenge when it comes to diseases of the brain is getting treatment across the blood-brain barrier and it is hoped that this new development could be key in treating diseases such as Parkinson’s, Muscular Dystrophy and Alzheimer’s.

The team of scientists at the University of Oxford used exosomes from mouse dentritic cells to cross that barrier. Studies found a 60% reduction in gene’s activity and it is hoped that the method could be modified to treat other conditions across the body. Lead Researcher, Dr Matthew Wood stated,  “We are working on sending exosomes to muscle, but you can envisage targeting any tissue. It can also be made specific by changing the drug used.”

Research will now test the treatment on mice with Alzheimer’s and see if their condition changes. It is hoped that trials will begin on human patients within  five years.

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Budget 2011: Increase of £100 million in Funding

As announced today, the government will be injecting an additional £100 million into scientific research in the UK.

“The Government will invest an additional £100 million in 2011-12 in science capital development to provide facilities for the commercialisation of research, accommodation for innovative SMEs and new research capabilities,” read the budget.

As well as this extra funding, plans for a ‘technology and innovation centre’ have also been revealed. This centre will conduct it’s own research and bring together work from institutions based in Rotherham, Coventry, Strathclyde, Sedgefield, Redcar and Bristol.

Looking for a job in science? Click here to search our UK science jobs online now.

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Novartis to Cut UK Pharmaceutical Jobs

As reported by the BBC, The Swiss-based pharmaceutical company, Novartis are reportedly planning to close their drug development and manufacturing operations in Horsham, West Sussex, leading to  hundreds of cuts to pharmaceutical jobs.

This site currently employees 950 staff and this is set to reduce to 400 within just two years. It produces approximately 60 different formulations of drugs. Staff will be retained who work on developing respiratory drugs in Horsham. Those focused on gastrointestinal medicines will be relocated to their units based in Cambridge, Massachusetts and Basel in Switzerland.

The announcement comes after a series of cuts by pharmaceutical companies across the UK. Including, Pfizer who are to close their research and development centre in Sandwich, Kent – potentially cutting up to 2,400 posts. In addition, both AstraZeneca and GlaxoSmithKline are shutting down sites across the UK.

Novartis have disputed the notion that their plans to close the Horsham site is linked to the decline in attractiveness of the UK in terms of innovation. General Manager, Sue Webb stated, “With significant changes in healthcare systems aimed to contain or cut cost, this critical assessment and the subsequent potential changes to the Novartis UK organisation are key to maintain significant investment in innovative drugs and our research efforts in the UK.”

The Swiss-based pharmaceutical company plan to maintain their manufacturing sites based in Grimsby, Liverpool and Dundee.

Are you looking for a new position in the UK Pharmaceutical Industry? Click here to search our current jobs now.

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A fun-packed National Science And Engineering Week

Dragons, bugs and solar power are part of the packed programme of events put together by the city’s two Universities to celebrate National Science and Engineering Week.

And with the workings of the human brain and lung also under the microscope at children-friendly lectures across the city, this year’s event is sure to appeal to people of all ages.

Sheffield’s two universities are joining forces once again to demonstrate to the public the fascinating world of science and technology, as National Science and Engineering Week takes place from Friday 11 March until Monday 20 March.

Sheffield is proud to host one of the largest programmes of Science week activities in the UK.

Among the highlights are:

  • a chance to try dragon boat racing on a machine assembled in the city’s Winter Gardens by engineers and sports researchers at Sheffield Hallam University
  • millions of creepy-crawlie bugs being put under the microscope at an Art In The Park event at Broadfield Park
  • a David Allen Booth memorial lecture examining  Brain Research with special attention to brain diseases such as epilepsy, Parkinson’s Disease and Alzheimers
  • a lecture on the University of Sheffield’s Project Sunshine, which aims to unite scientists to harness the power of the sun in a bid to tackle the increasing food and energy needs of the world’s population
  • INSPIRATION – a lecture inspired by Winter Gardens exhibition Primitive Streak in which experts from the University of Sheffield examine the human lung

National Science and Engineering Week is organised by the regional committee of the British Science Association and South Yorkshire’s programme is one of the largest in the UK, with more than  400 events taking place throughout the week.

The programme, spearheaded by Sheffield Hallam’s Centre for Science Education, includes a series of lectures, exhibitions and hands-on activities designed to bring members of the general public, schools and colleges into contact with inspiring displays of science and technology.

Dr Richard Walton, Reader in education at Sheffield Hallam University and Director of STEMPOINT, which is coordinating the events, said: “National Science and Engineering Week is a national celebration of the very best of British research and innovation. Once again South Yorkshire’s programme is one of the largest in the country and is sure to be an excellent opportunity for people to learn new and exciting things about science and technology. We are very grateful for the efforts made by the large team of volunteers who consistently provide exciting and stimulating events for children and the public.”

Professor  Anthony Ryan OBE, Pro Vice-Chancellor for Science at the University of Sheffield, said: “We are delighted that once again we can take part in the huge outreach to primary and secondary schools and the great British public during National Science and Engineering Week.  The event gives thousands of people the chance to get involved in a wide range of subjects spanning mathematics, physics, chemistry, biology, psychology and engineering, allowing us to share the thrill of looking at life’s interesting questions from the perspective  of a scientist or engineer.  Laurie to check this para with  UoS

 

Notes to editors:For a full programme of events and ticket information visit http://www.scienceweeksy.org.uk/

National Science and Engineering Week is coordinated by the British Science Association and funded by the Department for Innovation, Universities and Skills (DIUS) in partnership with Engineering Technology Board (ETB). It aims to celebrate science and its importance to everyday life, providing an opportunity for people of all ages across the UK to take part in science, engineering and technology activities.

Project Sunshine, led by the Faculty of Science at the University of Sheffield aims to unite scientists across the traditional boundaries in both the pure and applied sciences to harness the power of the sun and tackle the biggest challenge facing the world today: meeting the increasing food and energy needs of the world´s population in the context of an uncertain climate and global environment change. It is hoped that Project Sunshine will change the way scientists think and work and become the inspiration for a new generation of scientists focused on solving the world´s problems.  The first international Project Sunshine conference, Shine, will take place from 13-14 September 2011 at Sheffield City Hall. For more information, visit: http://shine.sheffield.ac.uk/

CK Science is the UK’s leading specialist scientific and engineering recruitment consultancy.

For more information about CK Science and its services, please visit the website www.ckscience.co.uk, call 0114 283 9956 or email info@ckscience.co.uk.

For press information and interviews: contact Laurie Harvey in the Sheffield Hallam Press Office on 0114 225 2621or Shemina Davis at the University of Sheffield, on 0114 2225339 or email shemina.davis@shef.ac.uk

Find all our recent releases at http://www.shu.ac.uk/news.

 

 

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Did You Know it’s National Science and Engineering Week Soon?

The National Science and Engineering Week will be kicking off between 11th and 20th March 2011. The event will focus around the theme of ‘communication’.

Thousands of events and activities will be taking place across the country with the aim of demonstrating how science and engineering relate to your everyday life.

Please see below for details of science events taking place near you:

To find out more about events taking place in your area, please visit the British Science Association website.

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CK Science to feature on The Guardian’s Live Q&A

CK Science are proud to announce that will be featuring on the panel of experts for The Guardian’s Live Q&A discussing the skills physics graduates have gained – and the career options available to them.

Along with the other expert panel members, Director at CK Science, Ashley Kirk, will be offering insight into the types of jobs physics graduates can get into and the skills you will need to get them. With 20 years of experience in dealing with scientific careers, Ashley is well placed to provide some invaluable advice.

So if you have recently graduated in a Physics related degree or are looking for a new position in the area, why not join the discussion. It’s taking place tomorrow at 1-4pm. Please click here to find out more and to join the discussion tomorrow.

We look forward to seeing you there!

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GSK to Pay Trainee Tuition Fees

As reported by The Telegraph, The global pharmaceutical company, GlaxoSmithKline (GSK), is to pay up to £27,000 university tuition fees for 50 to 100 of their graduate trainees. They are the first company to announce help recruits in this way.

The company’s chief executive, Andrew Witty announced the news on Sky News. He stated that the scheme was not restricted to scientists, chemists and pharmacists, but will also be available to lawyers, economists and all of the other top class graduates that could help the pharmaceutical company.  He said, “The biggest reason we are doing this is that we want to get the absolute best possible graduates we can to work for GSK,” he told the programme. This is a great way for us to try and ensure we get that next brilliant scientist.”

As of next year, university tuition fees will triple for undergraduates so this is great news for budding scientists who are interested in working in the Pharmaceutical industry.

It is hoped that the announcement of GSK’s scheme will will encourage other companies to follow suit and help their recruits with crippling tuition fees. Thus ensuring that potential top talent will continue with their education.

GSK’s programme will costs them around £3 million per year and trainees will be required to stay with the company for several years until the fees have be repaid.

Are you looking for a new position in the Pharmaceutical Industry? Click here to search our current pharmaceutical jobs online now.

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Chemical Industry Jobs in the South of England

Analytical Chemist / Analyst

  • Salary: £16,000 – £30,000
  • Start Date: ASAP
  • Telephone: 01438 723 500
  • Email: abolton@ckscience.co.uk
  • Location: London or Hampshire
  • Consultant Name: Andrew Bolton

CK Science is currently representing several organisations in the South of the UK who are looking for Analytical Chemists / Analysts to join their Petrochemical / Oil & Gas Testing Laboratories based in the London and Hampshire regions.

Working as an Analytical Chemist / Analyst, you will be responsible for the analysis of chemical samples, using a wide range of physical property analysis (ASTM, IP) and analytical techniques such as ICP, AA, GCMS, HPLC and GC. Working in a busy, customer facing laboratory, you will also be required to monitor quality standards in the laboratory (UKAS, ISO) as well as liaise with the customer surrounding results of tests.

This is an outstanding opportunity to join a leading Testing Laboratory, which in return offers an attractive salary and benefits package.

To be considered for this role, you will have a degree in Chemistry, Analytical Chemistry or a related discipline (or equivalent). It is essential to have a demonstrated background in an Analytical function within the Oil & Gas, Petrochemical, Chemical or Environmental industries.


Development Engineer – Inks, Herts, Cambs

  • Salary: £Negotiable
  • Start Date: ASAP
  • Telephone: 01438 723 500
  • Email: abolton@ckscience.co.uk
  • Location: Hertfordshire / Cambridgeshire
  • Discipline: Engineering
  • Consultant Name: Andrew Bolton

Our client, a leading Inks Technology organisation, are currently looking for a Development Engineer to join their growing R&D Team based from their site in the Hertfordshire & Cambridgeshire region.

Working as a Development Engineer, you will be responsible for all aspects of design, assembly and testing of the organisations printing systems. Your duties will include the design (CAD) and prototyping of systems in line with customer requirements; implementing technology development as well as carrying out testing and validation of subsystems and systems solutions through empirical testing and analytical models.

This is an outstanding opportunity to join an innovative, leading Inks Technology organisation, which in return offers an attractive salary and benefits package.

To be considered for this role, you will have a degree in an Engineering discipline – Mechanical, Electronic, Materials, Production – (or equivalent) and demonstrated experience in a Development Engineer function including knowledge of CAD, gained in an Inks industry.

Not quite what you’re looking for? Click here to search our current Chemical industry jobs online now: https://ckscience.co.uk/search/

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BioCity Boot Camp (Formerly Bioentrepreneur School)

  • Date: 6th – 8th April 2011
  • Venue: BioCity Nottingham

A new-style BioCity Boot Camp will take place at BioCity Nottingham on 6th – 8th April and is ideal for anyone in the life sciences who has the germ of a business idea.

Delivered by seasoned entrepreneurs and business professionals, the Boot Camp will help delegates develop a business mind-set that will be invaluable on their road to future success.

The three-day programme includes practical exercises; case studies; lively discussion; networking; mentoring and presentations. Intensive and challenging, individual sessions build towards a friendly ‘Dragons Den’ style competitive pitch to a panel of industry experts.

Suited to recent graduates, post-docs and academic researchers – or simply those with experience within a larger organisation who feel the urge to break out on their own – the Boot Camp is ideal for anyone looking to commercialise a particular science or a great idea.

With sponsorship support from AstraZeneca, PERA and AdamsonJones the Boot Camp will help delegates develop their business know-how, and give them the confidence to reach their potential in this rapidly changing business environment.

A number of fully-funded places are available for Astrazeneca employees.

For more information and to register your interest, visit http://bootcamp.biocity.co.uk

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Reckitt Benckiser to be sued by NHS

As reported by the BBC, Reckitt Benckiser, the manufacturer of the hearburn medicine Gaviscon, will be sued by the NHS in England.

In October 2010, The Office of Fair Trading stated that the company had restricted competition in the supply of heartburn medicines in the UK. Once’s Gaviscon’s patent had expired, Reckitt’s withdrew the original Gaviscon from the NHS and transferred them to Gaviscon Advamce Liquid, thus not giving pharmacists the option to chose a cheaper generic alternative.

High court documents show that Reckitt Benckiser is to be sued by all 10 Strategic Health Authorities, total of 144 Primary Care Trusts in England and by the Secretatory of State of State for Health, Andrew Lansley.

Both the Department and Health and Reckitt Becnkiser have refused to comment on the subject.

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Nestlé Acquires UK Pharma Company

A reported by The Press Association, the Swiss food giant, Nestlé have acquired the London-based CM&D Pharma in a bid to expand it’s science-based nutritional treatments.

The pharma company, which was founded in 2007 have developed a new chewing gum, Fostrap, which could help the sufferers of kidney disease. The chewing gum works by removing high levels of phosphate from kidney disease patients which is collected in the saliva as they chew the gum.

The pharmaceutical company also makes products for those with intestinal pain and colon cancer.

Luis Cantarell, president and chief executive of Nestle Health Science, said: “This acquisition is an excellent fit with Nestle Health Sciences strategic goal of being a pioneer in the promising area of science-based nutrition.”

Are you looking for a new position in the pharmaceutical industry? Click here to search our current pharma jobs online now.

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