As reported by Pharmiweb, current research suggests that Vitamin D supplements may have wide-ranging anti-ageing properties including the preservation of eyesight. The research is still at an early stage however research scientists believe it could have important implications for human health. Boosting the intake of vitamin D may have broad anti-ageing effects and in particular help prevent loss of vision and blindness in older people.
During the research study middle-aged mice treated with the vitamin for six weeks underwent changes in their eyes that led to improved vision. Levels of amyloid beta, a toxic protein linked to Alzheimer’s disease and known to be a hallmark of ageing, were also reduced in the animals’ eyes and blood vessels.
Lead scientist Professor Glen Jeffery, from the Institute of Ophthalmology at University College London, said: “Finding that amyloid deposits were reduced in the blood vessels of mice that had been given vitamin D supplements suggests that vitamin D could be useful in helping to prevent a range of age-related health problems, from deteriorating vision to heart disease.”
Heather Deagle is looking for a Protein Scientist to join a major biotechnology company based in the Central Belt of Scotland.
Responsibilities:
The successful candidate for this Protein Scientist role will join a busy team working on scale-up and GMP manufacture of protein conjugates. They will synthesise protein conjugates and develop purification protocol, using HPLC based techniques for characterisation. They will also participate in writing process instruction sheets for manufacturing, validating processes and equipment and in technical support of manufacturing activities.
Skills required:
The ideal candidate for this Protein Scientist role will have a good understanding of general protein handling techniques, together with an appropriate qualification in Biochemistry or similar.
How to apply:
For more information or to apply for this Protein Scientist role please contact Heather Deagle on 0191 384 8905 or email hdeagle@ckscience.co.uk. Please quote reference DH23192 in all correspondence.
As reported by BBC News Online, Research Scientists revealed a potential new malaria vaccine has shown promise in animal studies, according to research. An Oxford University team is to start safety trials in human volunteers after lab tests showed the vaccine works against all strains of the parasite.
UK scientists recently found the route malaria uses to enter blood cells. They hope to target this pathway in a new approach to developing a vaccine against malaria, which kills hundreds of thousands of people a year. Several potential malaria vaccines are already being tested in clinical trials; although no vaccine has yet been licensed for use.
One possibility is to exploit a recently-discovered potential weakness in the parasite’s life cycle. A team at the Sanger Institute found in November that a single receptor on the surface of red blood cells and a substance known as “PfRh5″ on the parasite are crucial to the success of malaria in invading blood cells.
Early lab tests suggest a vaccine against the protein may prove effective, at least in animals. Dr Sandy Douglas is a Wellcome Trust Clinical Research Training Fellow from the University of Oxford told the BBC: “We have found a way of making antibodies that kill all different strains of malaria parasites. This is still early phase research in animals. The next step is to do clinical trials in people.”
If safety tests of the vaccine prove successful, clinical trials in patients could begin within the next two to three years, says the Oxford team.
Carrie Ann Bell at CK Science presents this week’s Candidate of the Week, a Bioanalyst. To find out more, watch her short video and read the description below.
This candidate has two years experience as a bionalayst working with LC-MS and a further four years experience as an immunoanalyst predominantly working with ELISAs and antibody assays in the pharmaceutical industry.
They were responsible for their own studies in method development, validation and stability testing to GLP standards.
This candidate is flexible to work throughout Scotland and Northern England and is immediately available for employment.
For more information, please contact Carrie Ann on 0191 384 8905 or email cbell@ckscience.co.uk.
- 1994 – David was Medical Director at Genzyme working on the Cystic Fibrosis Gene Therapy program.
- He has also been the president of the Global Rare Disease Business and looked into the global launches of Aldurazyme, Fabrazyme and Myozyme.
- 2009 – David became the Chief Operating Officer of Genzyme
Meeker’s appointment to CEO will drive Genzyme’s push to incorporate the Rare Disease business and the Multiple Sclerosis franchise. He will join the Group Management Committee of Sanofi and report to Sanofi CEO, Christopher A. Viehbacher. Speaking of the news, Viehbacher stated, ”After working closely with David over the past six months, I am confident that he is the best person to lead Genzyme.”
Jason Johal at CK Science is currently recruiting for a Senior Virologist to join an established CRO based in London. Please watch his video below and read the job description below.
The role:
As Senior Virologist you will be responsible for liaising with the Associate Director of Virology and performing the development, optimisation and validation of new technologies such as assays, equipment, writing and reviewing publications and training of staff.
Responsibilities:
Assisting in the virus manufacturing processes and template protocols, including determination of release criteria and writing SOPs
Providing input into pre-clinical and clinical studies as it relates to virology expertise
Profiling the company as the leading resource and a preferred partner for the biotech and pharmaceutical industries
Participating in research programs in the field of respiratory and related infectious disease research
Providing Business Development support in the securing of clinical and translational research projects
Establishing budgets and determining resource needs for experimental work
Writing and reviewing publications working with clients and other collaborators so as to showcase research in appropriate peer reviewed journals
The ideal candidate:
Jason is looking for candidates with the following skills, experience and qualifications:
PhD qualified (or equivalent) in Biological Science
A member of a relevant professional body
Good working knowledge of GLP/GCP standards
Exceptional scientific research competencies
the ability to professionally advise and scientifically educate colleagues
Experienced in applying theoretical and working knowledge of virology in their daily work
Customer relationship skills are highly desirable
How to apply:
For more information or to apply for this Senior Virologist position, please contact Jason Johal at CK Science on 01438 723 500 or email jjohal@ckscience.co.uk. Please quote reference ST22966 in all correspondence.
The London Science Festival, which is taking place between 19th-23rd October, will cover ten venues with 30 separate science-related events. Here are some of the highlights:
Science Museum Lates - The festival comes to a close at the Science Museum’s monthly Lates evening, this time themed around climate change. FREE
For more information, please click here to visit the London Science Festival website. You can also follow the festival on Twitter: @LondonSciFest, or follow the hashtag #LSF11 throughout the event.
Hannah Milward is looking for an experienced medical devices Product Evaluation Engineer to join a international medical devices organisation with a reputation for developing innovative and cutting edge products within this dynamic industry.
Responsibilities:
The primary objective of this Process Evaluation Engineer role is to improve the success of New Product Developments (NPD). The PE Engineer has responsibility for the generation of documentation and conduct of testing to support PE activities within NPD projects. The PE Engineer shall ensure that valid and robust data is obtained and documented during execution of validation and verification activities.
Key responsibilities of this role are:
Produce design verification protocols, reports and perform the product testing where necessary.
Design, develop and validate appropriate test methods
Participate in NPD phase reviews, presenting the results and progress summaries of activities for which they are responsible.
Ensure clinical model definition – translation of the intended clinical usage of a device into a definition in quantifiable engineering terms of the operational and environmental conditions that the device must with stand
Participate in risk management and FMEA exercises.
Review and contribute to the necessary design input documents
Interface with design, marketing, clinical, manufacturing and quality teams to ensure the PE function is fully integrated within the NPD team
Conduct programmes for extended life / reliability testing of new products
Analyse and report on Customer Enquiries
All other essential related duties as required
Qualifications & skills required:
To be considered for this Product Evaluation Engineer role you will possess the following:
Degree or equivalent calibre in science, engineering or technology discipline with demonstrable relevant experience, preferably within the medical device industry
Experience of quality or product test fields
Good organisational skills
Attention to detail
Concern for quality and standards
Customer focus
How to apply:
For more information or to apply for this Process Evaluation Engineer role please contact Hannah Milward at CK Science on 0114 2839956 or hmilward@ckcience.co.uk. Please quote reference SH22946 in all correspondence.
Naynesh Mistry is looking to recruit a Product Development Manager (R&D) to join a leader in the manufacturer and supply of wet wipes to work at their site based in North Wales on a permanent basis.
Job Summary:
As a Product Development Manager (R&D) you will take an active role in the company’s New Product Development activity for consumer products through research and product development and to provide a professional technical support service to the company.
Job Scope:
To be a member of the Research & Development team and, in conjunction with other members, develop and implement plans for successful new product development for the business.
To develop commercial products in response to customer requests.
To be responsible for the technical support & formulation development for a number of customer accounts (including some retailers & brands).
To develop products, ensuring that they can meet the proposed claims and are compliant with the relevant regulations.
Responsibilities:
The main duties and responsibilities of this Product Development Manager (R&D) role include:
Manage new product development formulations from laboratory scale through to commercialisation, ensuring that accurate records are kept of the work done.
Manage Research & Development trials, with input from Manufacturing and Engineering, to plan, organise and implement material, product and processing trials.
Represent the Company with Customers (Internal & External) and Suppliers ensuring that a professional technical Customer Liaison and Support Service is provided.
Manage assigned projects to ensure product performance and safety and managing assigned projects from initiation to completion, meeting the required timescales.
Manage the introduction of new products by organising/creating raw material, product and customer specifications.
Ensure that adequate formulation and product stability trials are conducted to ensure product’s shelf life.
Ensure that new products, samples and materials are evaluated thoroughly and that adequate claim support data is generated.
Manage the development of tests and test methods for new materials, products and processes and to simplify current practices.
Product safety testing and validation and Maintain an up to date knowledge of the testing and verification of product support claims.
Help to identify the appropriate raw material/chemical suppliers who can service the business.
Qualifications and Experience:
The ideal candidate for this Product Development Manager (R&D) role will be educated to degree level in Chemistry or equivalent and have experience with dealing with retailers. Experience of having worked for a contract manufacturer (FMCG) and Formulation experience of Cosmetic products (toiletries) is essential. The successful candidate should also have experience in the development and management of Personal Care consumer products as well as working within an R&D role group supporting new product launches.
How to apply:
For more information or to apply for this role please contact Naynesh Mistry on 0114 2839956 or email nmistry@ckscience.co.uk. Please quote reference SH22908 in all correspondence.
Barney Smith is currently looking for a Shift Manager to join a world leading manufacturer at their site in Scotland.
The Job:
The successful candidate for this Shift Manager role will report to the Operations manager. The company require a manager to oversee the manufacturing team working continental 6 on, 4 off. This is an excellent opportunity to work in an influential role within one of the world’s leading manufacturing companies.
Responsibilities:
As a Shift Manager you will be responsible for total leadership of the shift operation including using effective staff resourcing, ensuring maximum production output levels, maintenance of high quality product standards and customer expectations, and be instrumental in continuous improvement initiatives.
Qualifications and Skills:
The ideal candidate must have a proven track record working within a food manufacturing environment at supervisory or management level and be entitled to work in the UK.
How to apply:
For more information or to apply for this Shift Manager role please contact Barney Smith on 0191 384 8905 or email bsmith@ckscience.co.uk. Please quote reference DH22907 in all correspondence.
by Pharmiweb, current research suggests that Vitamin D supplements may have wide-ranging anti-ageing properties including the preservation of eyesight. The research is still at an early stage however research scientists believe it could have important implications for human health. Boosting the intake of vitamin D may have broad anti-ageing effects and in particular help prevent loss of vision and blindness in older people.
